Paraneoplastic syndromes revealing ovarian teratoma in young and menopausal women: report of two cases
نویسندگان
چکیده
Paraneoplastic syndromes are a heterogeneous group of clinical and biological manifestations caused by underling neoplasms. They can reveal ovarian teratoma which express neuroendocrine proteins, or contain mature or immature neural tissue inducing an autoimmune response. The etiological investigation is then crucial to early identification of the tumor in order to optimize the prognosis and to limit neurological sequelae. In case of ovarian teratoma, management is essentially based on surgical resection sometimes associated with immunotherapie. We report two new cases of ovarian teratoma revealed by paraneoplastic syndromes in young and menopausal woman.
منابع مشابه
P-174: Good Pregnancy Outcome after Prenatal Exposure to Bleomycin, Etoposide and Cisplatin for Ovarian Immature Teratoma: A Case Report and Literature Review
Background: The administration of bleomycin plus etoposide and cisplatin during pregnancy is rare. Materials and Methods: We describe a case with good pregnancy outcome after exposure to these chemotherapeutic agents at the third trimester of pregnancy. Results: Pregnant woman with stage IIIc immature teratoma underwent surgical staging, and received two cycles of bleomycin, etoposide and cispl...
متن کاملLongitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.
Paraneoplastic myelitis is a rare inflammatory disorder most frequently associated with solid tumors or lymphoproliferative disorders. Patients often harbor onconeuronal antibodies and their prognosis is usually poor. Here we report a 42-year old woman with longitudinally extensive transverse myelitis and aquaporin-4 (AQP4) antibodies that led to the diagnosis of ovarian teratoma. After tumor r...
متن کاملSquamous Cell Carcinoma Arising From a Mature Cystic Teratoma of Ovary: A Rare Case
Mature cystic teratoma accounts for 10-20 % of all ovarian tumors. Malignant transformation is very rare in mature cystic teratoma, its incidence being 1-2% and is commonly seen in post menopausal women with tumor size larger than 10 cm. Pre-operative diagnosis of this entity is difficult due to non specific clinical & radiological features and no specific tumor markers. Malignant change occurs...
متن کاملHigh Grade B- Cell Non- Hodgkin’s Lymphoma Arising in a Mature Cystic Teratoma of the Ovary: A Case Report
Mature cystic teratoma (MCT) is the most common type of ovarian germ cell tumor occurring in females of reproductive age. It is typically benign, but rare malignant transformations have been reported in 1-2% of the cases. Among a wide variety of malignancies arising in MCTs, high grade lymphomas are the least common. We present a case of a 45- years -old female with a unilateral adnexal ma...
متن کامل